acumen explorer laser scanning fluorescence microplate cytometer (SPT Labtech)
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SPT Labtech
acumen explorer laser scanning fluorescence microplate cytometer
Acumen Explorer Laser Scanning Fluorescence Microplate Cytometer, supplied by SPT Labtech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/acumen+explorer+laser+scanning+fluorescence+microplate+cytometer/us10450317-152-4-10
Average 86 stars, based on 1 article reviews
Acumen Explorer Laser Scanning Fluorescence Microplate Cytometer, supplied by SPT Labtech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/acumen+explorer+laser+scanning+fluorescence+microplate+cytometer/us10450317-152-4-10
Average 86 stars, based on 1 article reviews
acumen explorer laser scanning fluorescence microplate cytometer - by Bioz Stars,
2026-09
86/100 stars
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Fluorescence:Article Title: Determination of Cell Colony Formation in a High-Content Screening Assay Article Snippet: Application of microplate cytometry thus offers significant benefits over alternative analytical methods in the search for novel chemotherapeutic agents. ( JALA 2005;10:203–6) INTRODUCTION Cell colony formation has been found to be a more sensitive parameter of toxicity than cell viability because colony formation is assessed while the cells are in a state of proliferation, and thus more *Correspondence: Wayne P. Bowen, Ph.D., TTP LabTech Ltd, R&D, Melbourn Science Park, Melbourn, Hertfordshire, UK; Phone: þ44 (0) 1763 262626; E-mail: Wayne.Bowen@ttplabtech.com 1535-5535/$30.00 Copyright c 2005 by The Association for Laboratory Automation doi:10.1016/j.jala.2005.06.001 at UNIV OF BIRMINGHjla.sagepub.comDownloaded from susceptible to toxic effects.1 Enumeration of colonies has been traditionally carried out using a semisolid agarose bilayer system in petri dishes and involves manual counting on a microscope.2–4 These soft agar colony formation assays have been widely used to determine growth and drug sensitivity of mammalian stem cells as well as fresh human tumor material.5 In general, use of these assays to determine drug sensitivity has been largely based upon subjective determination of the number of colonies which exceed an arbitrary size (often 60 mm in diameter) in drug-treated cultures relative to that seen in control cultures.5 Recent advances have provided automatic number counting of bacterial and mammalian colonies using digital color cameras, which with the accompanying software, allows a number of different colony colors to be distinguished.6–8 More advanced image analysis systems are unable to offer colony counting on a whole well basis due to the imaging of small well areas, typically less than 1 mm 1 mm. .. The Article Title: Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor. Article Snippet: Interference with DNA damage checkpoints has been demonstrated preclinically to be a highly effective means of increasing the cytotoxicity of a number of DNA-damaging cancer therapies.. Cell cycle arrest at these checkpoints protects injured cells from apoptotic cell death until DNA damage can be repaired.. In the absence of functioning DNA damage checkpoints, cells with damaged DNA may proceed into premature mitosis followed by cell death. Cytometry:Article Title: Determination of Cell Colony Formation in a High-Content Screening Assay Article Snippet: Application of microplate cytometry thus offers significant benefits over alternative analytical methods in the search for novel chemotherapeutic agents. ( JALA 2005;10:203–6) INTRODUCTION Cell colony formation has been found to be a more sensitive parameter of toxicity than cell viability because colony formation is assessed while the cells are in a state of proliferation, and thus more *Correspondence: Wayne P. Bowen, Ph.D., TTP LabTech Ltd, R&D, Melbourn Science Park, Melbourn, Hertfordshire, UK; Phone: þ44 (0) 1763 262626; E-mail: Wayne.Bowen@ttplabtech.com 1535-5535/$30.00 Copyright c 2005 by The Association for Laboratory Automation doi:10.1016/j.jala.2005.06.001 at UNIV OF BIRMINGHjla.sagepub.comDownloaded from susceptible to toxic effects.1 Enumeration of colonies has been traditionally carried out using a semisolid agarose bilayer system in petri dishes and involves manual counting on a microscope.2–4 These soft agar colony formation assays have been widely used to determine growth and drug sensitivity of mammalian stem cells as well as fresh human tumor material.5 In general, use of these assays to determine drug sensitivity has been largely based upon subjective determination of the number of colonies which exceed an arbitrary size (often 60 mm in diameter) in drug-treated cultures relative to that seen in control cultures.5 Recent advances have provided automatic number counting of bacterial and mammalian colonies using digital color cameras, which with the accompanying software, allows a number of different colony colors to be distinguished.6–8 More advanced image analysis systems are unable to offer colony counting on a whole well basis due to the imaging of small well areas, typically less than 1 mm 1 mm. .. The Article Title: Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor. Article Snippet: Interference with DNA damage checkpoints has been demonstrated preclinically to be a highly effective means of increasing the cytotoxicity of a number of DNA-damaging cancer therapies.. Cell cycle arrest at these checkpoints protects injured cells from apoptotic cell death until DNA damage can be repaired.. In the absence of functioning DNA damage checkpoints, cells with damaged DNA may proceed into premature mitosis followed by cell death. Staining:Article Title: Determination of Cell Colony Formation in a High-Content Screening Assay Article Snippet: Application of microplate cytometry thus offers significant benefits over alternative analytical methods in the search for novel chemotherapeutic agents. ( JALA 2005;10:203–6) INTRODUCTION Cell colony formation has been found to be a more sensitive parameter of toxicity than cell viability because colony formation is assessed while the cells are in a state of proliferation, and thus more *Correspondence: Wayne P. Bowen, Ph.D., TTP LabTech Ltd, R&D, Melbourn Science Park, Melbourn, Hertfordshire, UK; Phone: þ44 (0) 1763 262626; E-mail: Wayne.Bowen@ttplabtech.com 1535-5535/$30.00 Copyright c 2005 by The Association for Laboratory Automation doi:10.1016/j.jala.2005.06.001 at UNIV OF BIRMINGHjla.sagepub.comDownloaded from susceptible to toxic effects.1 Enumeration of colonies has been traditionally carried out using a semisolid agarose bilayer system in petri dishes and involves manual counting on a microscope.2–4 These soft agar colony formation assays have been widely used to determine growth and drug sensitivity of mammalian stem cells as well as fresh human tumor material.5 In general, use of these assays to determine drug sensitivity has been largely based upon subjective determination of the number of colonies which exceed an arbitrary size (often 60 mm in diameter) in drug-treated cultures relative to that seen in control cultures.5 Recent advances have provided automatic number counting of bacterial and mammalian colonies using digital color cameras, which with the accompanying software, allows a number of different colony colors to be distinguished.6–8 More advanced image analysis systems are unable to offer colony counting on a whole well basis due to the imaging of small well areas, typically less than 1 mm 1 mm. .. The Article Title: Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor. Article Snippet: Interference with DNA damage checkpoints has been demonstrated preclinically to be a highly effective means of increasing the cytotoxicity of a number of DNA-damaging cancer therapies.. Cell cycle arrest at these checkpoints protects injured cells from apoptotic cell death until DNA damage can be repaired.. In the absence of functioning DNA damage checkpoints, cells with damaged DNA may proceed into premature mitosis followed by cell death. other:Article Title: Notch pathway signaling inhibitor compounds Article Snippet: Plates are scanned with ACUMEN EXPLORERTM Laser-scanning fluorescence microplate cytometer ( Article Title: LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models Article Snippet: Colony counts were quantified on |